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Reactive arthritis

Evidence: Immune-mediated

Names

Reiter’s syndrome
ReA
Fiessinger-Leroy disease

Description

Reactive arthritis is an autoimmune condition classified in the family of spondyloarthritis. It is a type of arthritis that is typically acute and is most frequently caused by infections from bacteria in the genitals or bowel.  Reactive arthritis symptoms usually last for between 3 and 12 months. However, in some individuals, subsequent flares may occur due to stress or infection. The condition may also become chronic in some individuals. Reactive arthritis may go unnoticed and heal on its own or it can cause pain in the joints. The knees and ankles are affected most often.

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Prevalence

US Cases: 250,000 - 340,000 [Hanova 2010]

Typical Age of onset

Typically men 20-30 years of age. Source: Hall (2018)

Symptoms

  • Joint swelling and pain, especially in knees, ankles, and feet

  • Tendon pain, especially at the base of the Achilles

  • Low back pain

  • Redness and irritation of eyes

  • Blurred vision and sensitivity to light

  • Rash on the feet or hands

  • Burning with urination 

  • Increased frequency of urination

  • Discharge with urination

  • Urinary tract inflammation 

  • Genital ulcers

  • Diarrhea

  • Red, waxy bumps on the palms or foot soles forming a rash

  • Fever

  • Fatigue

  • Weight loss