Autoimmune diseases are often thought of as diseases affecting adults and the elderly. However, there are various autoimmune diseases that can begin in childhood, such as juvenile idiopathic arthritis and juvenile dermatomyositis. The story of Jamee Emens' family shows exactly that, as Jamee's son, Jack, spent his early years of life in and out of hospitals with respiratory issues until Jack's father met Dr. Fayez K. Ghishan, who diagnosed Jack with eosinophilic esophagitis.
Jack is a triplet and isn't the only one in his family to be diagnosed with an autoimmune disease. His two sisters, Peyton and Cameron, were also diagnosed with several autoimmune conditions, including type 1 diabetes, vitiligo, myasthenia gravis, and more. His family highlights the role genetics can play in the emergence of autoimmune diseases, and underscores the importance of whole genome sequencing.
Whole genome sequencing involves collecting a person's DNA from a blood sample or cheek swab and analyzing it to understand how genes influence disease. Once the DNA is broken down and analyzed, geneticists compare the data to a reference genome to find any mutations or variants in the DNA. In 2022, the University of Arizona's Steele Children’s Research Center obtained a machine that allows for large-scale whole genome sequencing. With these advances in technology, we're one step closer to understanding the biological foundations of autoimmune diseases. These breakthroughs hold the promise of more personalized treatment options tailored to each individual's genetic makeup, offering hope for better outcomes for patients with autoimmune conditions.
At Autoimmune Registry Inc., we are dedicated to supporting research by collecting essential data and statistics on autoimmune diseases. Our comprehensive data collection can help researchers connect phenotypic characteristics—observable traits or features of individuals, such as symptoms, physical attributes, and responses to treatments—with genetic information.
To support the Autoimmune Registry, please share our information with others who have autoimmune diseases. Donations are also greatly appreciated!
We are also hosting a webinar on Wednesday, October 23rd from 12-1 pm ET with Own MG to help people have a better understanding of myasthenia gravis. To learn more, visit our website. To register, click here.
