Myasthenia gravis
Evidence: Antibody
Names
Myasthenia gravis
Acquired myasthenia
Autoimmune myasthenia gravis
MG
Description
Myasthenia gravis is a neuromuscular disorder characterized by muscle weakness and fatigue. It occurs when the antibodies block the junction between the nerve and skeletal muscles, which are responsible for voluntary body movements.
Patient Groups
Prevalence
US Cases: 48,000 - 64000 [Keesey 2004] by reference.
Typical Age of onset
20-80 years
Symptoms
Weakness in the arm, hands, fingers, neck
Drooping of one or both eyelids.
Double vision
Impaired speech
Difficulty in swallowing
Difficulty in chewing
Change in facial expression
Shortness of breath
Source: Mayo Clinic