Paroxysmal nocturnal hemoglobinuria
Evidence: Unconfirmed
Names
Paroxysmal nocturnal hemoglobinuria
Description
Paroxysmal nocturnal hemoglobinuria is a rare blood disorder caused when a protein is missing from a person’s blood due to a mutation in a gene. Without the protein, the body’s immune system attacks the red blood cells and breaks them apart.
Patient Groups
Bloggers
None found
Prevalence
US Cases: 300-500 [Jalbert 2019]
Typical Age of onset
40 to 50 years old
Symptoms
Dark or tea colored urine
Low red blood cell count (anemia)
Fatigue
Headaches
Trouble breathing when you exercise
Irregular heartbeat
Muscle spasms
Pain in your belly
Spasms in your throat that can make it hard to swallow
Erectile dysfunction
