`

Linear IgA disease

Evidence: Antibody

Names

Linear IgA disease
Linear IgA bullous disease
Chronic bullous dermatosis of childhood
Linear IgA dermatosis

Description

Linear IgA disease causes blisters to form deep in the skin. It can affect the skin and mucus membranes such as the mouth and genitals. Its name comes from the image produced during a skin biopsy in which a line of IgA antibodies can be found just below the outer layer of skin (the epidermis).

Patient Groups

None

Bloggers

None

Prevalence

US Cases: 150 - 700 [Fortuna 2012].

Typical Age of onset

It affects young children usually before the age of 5 and adults usually over the age of 40.

Symptoms

  • Blisters or lesions in the skin of the trunk, scalp, face, and limbs, or mucus membranes (mouth, anus, or genitals) in a clustered arrangement

  • Lesions are often itchy and may burn

  • In children, the perineum is often involved

References

The Australasian College of Dermatologists                                  

Medscape

Profile by Laavanya Pasupuleti