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Bullous pemphigoid

Evidence: Antibody

Names

Bullous pemphigoid

Description

Bullous pemphigoid is a rare, autoimmune, chronic skin disorder characterized by blistering. This disorder occurs most frequently in elderly people. Generalized blistering occurs in and under the upper layers of the skin and usually subsides spontaneously within several months or years. In some rare cases of Bullous pemphigoid, complications such as pneumonia may develop.

Bloggers

None found.

Prevalence

US Cases: 82,000 [Kridin 2018]

Typical Age of onset

Average age at onset of 65 years.

Symptoms

  • Large blisters on lower abdomen, groin, upper thighs & arms that don't easily rupture when touched

  • Itchy, hive-like rash

  • Blisters or sores in mouth

  • Blisters on eyes

  • Wart-like plaques on areas of the skin, such as the armpit, neck, groin, and breasts (very uncommon)

  • Flare/remission pattern to symptoms

Notes:
1. In childhood-onset bullous pemphigoid associated with vaccination, the bullous lesions predominantly affect the palms, soles, and face

2. In infants, blisters tend to occur frequently on the palms, soles, and face, only rarely affecting the genital areas