Bullous pemphigoid
Evidence: Antibody
Names
Bullous pemphigoid
Description
Bullous pemphigoid is a rare, autoimmune, chronic skin disorder characterized by blistering. This disorder occurs most frequently in elderly people. Generalized blistering occurs in and under the upper layers of the skin and usually subsides spontaneously within several months or years. In some rare cases of Bullous pemphigoid, complications such as pneumonia may develop.
Patient Groups
Bloggers
None found.
Prevalence
US Cases: 82,000 [Kridin 2018]
Typical Age of onset
Average age at onset of 65 years.
Symptoms
Large blisters on lower abdomen, groin, upper thighs & arms that don't easily rupture when touched
Itchy, hive-like rash
Blisters or sores in mouth
Blisters on eyes
Wart-like plaques on areas of the skin, such as the armpit, neck, groin, and breasts (very uncommon)
Flare/remission pattern to symptoms
Notes:
1. In childhood-onset bullous pemphigoid associated with vaccination, the bullous lesions predominantly affect the palms, soles, and face
2. In infants, blisters tend to occur frequently on the palms, soles, and face, only rarely affecting the genital areas
References
Updated January 2023