`

Autoimmune enteropathy

Evidence: Antibody

Names

Autoimmune enteropathy

Description

Autoimmune enteropathy is an extremely rare disease characterized by diarrhea that does not respond to treatment and may require intravenous feeding to sustain the patient. It is diagnosed most frequently in infants, and it is marked by the presence of antibodies to the enzyme tryptophan hydroxylase, which performs a number of functions in human biology, Autoimmune enteropathy is increasingly being diagnosed in adults, but the symptoms are the same as many more common diseases, so correct diagnosis is difficult. It is more frequently diagnosed in patients already diagnosed with other autoimmune diseases such as autoimmune polyendocrine syndrome 1.

Patient Groups

None

Bloggers

None

Prevalence

Extremely rare (under 100 cases estimated). No specific estimates of prevalence provided [Ruemmele 2015]

Typical Age of onset

Most common in infants but more diagnoses in adults are being reported. [Ruemmele 2015]

Symptoms

  • Diarrhea / loose watery stools all the time

  • Poor weight gain and weight loss

  • Decreased urine output

  • Frequent infections

  • Occasional blood in the stool

  • Skin rash