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Microscopic colitis

Evidence: Unconfirmed

Names

Microscopic colitis

Description

Microscopic colitis occurs with severe inflammation of the large intestine, or the colon. It results in persistent and watery diarrhea. Microscopic colitis can’t be identified with a colonoscopy, so tissue samples from the colon must be examined under a microscope. There are three different subtypes:

  • Collagenous colitis results from a thick layer of the protein collagen developing in the tissue.

  • Lymphocytic colitis results from an increase in white blood cells in the tissue.

  • Incomplete microscopic colitis is a combination of collagenous and lymphocytic colitis.

It is under debate whether collagenous and lymphocytic colitis are different phases of the same condition. 

Bloggers

None

Prevalence

US Cases: 330,000 [Pardi 2006]

Typical Age of onset

60-70 years of age 
Source: Wickbom et al (2017)

Symptoms

  • Chronic water diarrhea

  • Abdominal pain, cramping, bloating

  • Weight loss

  • Nausea

  • Fecal incontinence

  • Dehydration